Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells

BACKGROUND: The objective of this study was to investigate the effects of interleukin-6 (IL-6) overexpression in androgen-dependent prostate cancer LNCaP cells on their phenotype under an androgen-deprived condition. METHODS: We established IL-6-overexpressing LNCaP (LNCaP/IL-6) by introducing the e...

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Detalhes bibliográficos
Main Authors: Terakawa, T, Miyake, H, Furukawa, J, Ettinger, S L, Gleave, M E, Fujisawa, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778549/
https://ncbi.nlm.nih.gov/pubmed/19844233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605358
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