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THE ROLES OF SYNTHESIS AND DEGRADATION IN DETERMINING TISSUE CONCENTRATIONS OF LACTATE DEHYDROGENASE-5

C(14)-labeled amino acids were incorporated in vivo into LDH-5 of rat tissues. Different amounts of LDH-5 in liver, heart muscle, and skeletal muscle resulted from differences in rates of both intracellular degradation and synthesis. Rate constants for LDH-5 synthesis were 65, 2, and 5 picomoles per...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Fritz, Paul J., Vesell, Elliot S., White, E. Lucile, Pruitt, Kenneth M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1969
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC277841/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5256233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.62.2.558
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