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Detecting natural selection by empirical comparison to random regions of the genome
Historical episodes of natural selection can skew the frequencies of genetic variants, leaving a signature that can persist for many tens or even hundreds of thousands of years. However, formal tests for selection based on allele frequency skew require strong assumptions about demographic history an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778377/ https://ncbi.nlm.nih.gov/pubmed/19783549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp457 |
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