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Reproducing the manual annotation of multiple sequence alignments using a SVM classifier

Motivation: Aligning protein sequences with the best possible accuracy requires sophisticated algorithms. Since the optimal alignment is not guaranteed to be the correct one, it is expected that even the best alignment will contain sites that do not respect the assumption of positional homology. Bec...

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Bibliografiske detaljer
Main Authors: Blouin, Christian, Perry, Scott, Lavell, Allan, Susko, Edward, Roger, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778337/
https://ncbi.nlm.nih.gov/pubmed/19770262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp552
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