Structure–Activity Relationship Studies for the Peptide Portion of the Bladder Epithelial Cell Antiproliferative Factor from Interstitial Cystitis Patients

We performed comprehensive structure–activity relationship (SAR) studies on the peptide portion of antiproliferative factor (APF), a sialylated frizzled-8 related glycopeptide that inhibits normal bladder epithelial and urothelial carcinoma cell proliferation. Glycopeptide derivatives were synthesiz...

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Detalhes bibliográficos
Main Authors: Kaczmarek, Piotr, Keay, Susan K., Tocci, Gillian M., Koch, Kristopher R., Zhang, Chen-Ou, Barchi, Joseph J., Grkovic, David, Guo, Li, Michejda, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778288/
https://ncbi.nlm.nih.gov/pubmed/18788730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8002763
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