N-hydroxybenzimidazole Inhibitors of the Transcription Factor LcrF in Yersinia: Novel Anti-Virulence Agents

LcrF, a Multiple Adaptational Response (MAR) transcription factor, regulates virulence in Yersinia pestis and Yersinia pseudotuberculosis. In a search for small molecule inhibitors of LcrF, an acrylic amide series of N-hydroxybenzimidazoles was synthesized, and the SAR (structure-activity relationsh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Oak K., Garrity-Ryan, Lynne K., Bartlett, Victoria J., Grier, Mark C., Verma, Atul K., Medjanis, Gabriel, Donatelli, Janice E., Macone, Ann B., Tanaka, S. Ken, Levy, Stuart B., Alekshun, Michael N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778250/
https://ncbi.nlm.nih.gov/pubmed/19708663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9006577
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak