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Group B Streptococcal Conjugate Vaccines Elicit Functional Antibodies Independent of Strain O-Acetylation

Recently, it was discovered that sialic acid residues on group B streptococcal (GBS) capsular polysaccharides (CPS) are O-acetylated. Since GBS vaccine development has focused on de-O-acetylated CPS, it became germane to investigate the influence of de-O-acetylated GBS vaccine formulations on functi...

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Detalhes bibliográficos
Main Authors: Pannaraj, Pia S., Edwards, Morven S., Ewing, Kristen T., Lewis, Amanda L., Rench, Marcia A., Baker, Carol J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778198/
https://ncbi.nlm.nih.gov/pubmed/19490960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.05.039
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