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Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif
BACKGROUND: Rho family GTPases are critical regulators of the cytoskeleton and affect cell migration, cell-cell adhesion, and cell-matrix adhesion. As with all GTPases, their activity is determined by their guanine nucleotide-bound state. Understanding how Rho proteins are activated and inactivated...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778012/ https://ncbi.nlm.nih.gov/pubmed/19956681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008045 |
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