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Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif

BACKGROUND: Rho family GTPases are critical regulators of the cytoskeleton and affect cell migration, cell-cell adhesion, and cell-matrix adhesion. As with all GTPases, their activity is determined by their guanine nucleotide-bound state. Understanding how Rho proteins are activated and inactivated...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Aghajanian, Amir, Wittchen, Erika S., Campbell, Sharon L., Burridge, Keith
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778012/
https://ncbi.nlm.nih.gov/pubmed/19956681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008045
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