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Interaction of CDK5RAP2 with EB1 to Track Growing Microtubule Tips and to Regulate Microtubule Dynamics

Mutations in cdk5rap2 are linked to autosomal recessive primary microcephaly, and attention has been paid to its function at centrosomes. In this report, we demonstrate that CDK5RAP2 localizes to microtubules and concentrates at the distal tips in addition to centrosomal localization. CDK5RAP2 inter...

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Main Authors: Fong, Ka-Wing, Hau, Shiu-Yeung, Kho, Yik-Shing, Jia, Yue, He, Lisheng, Qi, Robert Z.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777926/
https://ncbi.nlm.nih.gov/pubmed/19553473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0009
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