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PROLYL-tRNA(Pro) IN THE A SITE OF SecM-ARRESTED RIBOSOMES INHIBITS THE RECRUITMENT OF tmRNA

Translational pausing can lead to cleavage of the A-site codon and facilitate recruitment of the tmRNA (SsrA) quality control system to distressed ribosomes. We asked whether A-site mRNA cleavage occurs during regulatory translational pausing using the Escherichia coli SecM-mediated ribosome arrest...

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Main Authors: Garza-Sánchez, Fernando, Janssen, Brian D., Hayes, Christopher S.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777889/
https://ncbi.nlm.nih.gov/pubmed/16968693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608052200
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