Inhibition of biliverdin reductase increases ANG II-dependent superoxide levels in cultured renal tubular epithelial cells

Induction of heme oxygenase-1 (HO-1) in the renal medulla increases carbon monoxide and bilirubin production and decreases ANG II-mediated superoxide production. The goal of this study was to determine the importance of increases in bilirubin to the antioxidant effects of HO-1 induction in cultured...

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Detalhes bibliográficos
Main Authors: Young, Shelby C., Storm, Megan V., Speed, Joshua S., Kelsen, Silvia, Tiller, Chelsea V., Vera, Trinity, Drummond, Heather A., Stec, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777783/
https://ncbi.nlm.nih.gov/pubmed/19759334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90933.2008
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