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Chemotherapy-induced kaolin intake is increased by lesion of the lateral parabrachial nucleus of the rat

Anticancer agents, such as cisplatin, stimulate nausea, vomiting, and behaviors indicative of malaise. Rats and mice do not possess a vomiting response, and, therefore, in these species, the ingestion of kaolin clay (a pica response) has been used as an index of malaise. In the rat, cisplatin-induce...

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Detalhes bibliográficos
Main Authors: Horn, Charles C., De Jonghe, Bart C., Matyas, Kathleen, Norgren, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777772/
https://ncbi.nlm.nih.gov/pubmed/19710391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00284.2009
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