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High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage

The mechanisms underlying the massive gastrointestinal tract CD4 T-cell depletion in human immunodeficiency virus (HIV) infection are not well understood nor is it clear whether similar depletion is manifest at other mucosal surfaces. Studies of T-cell and virus dynamics in different anatomical site...

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Detalhes bibliográficos
Main Authors: Brenchley, JM, Knox, KS, Asher, AI, Price, DA, Kohli, LM, Gostick, E, Hill, BJ, Hage, CA, Brahmi, Z, Khoruts, A, Twigg, HL, Schacker, TW, Douek, DC
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777611/
https://ncbi.nlm.nih.gov/pubmed/19079160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2007.5
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