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Reduced Milk Triglycerides in Mice Lacking Phosphoenolpyruvate Carboxykinase in Mammary Gland Adipocytes and White Adipose Tissue Contribute to the Development of Insulin Resistance in Pups

Obesity and type 2 diabetes are growing problems worldwide in adults and children. In this study, we focused on understanding the patterning of insulin resistance as a result of altered perinatal nutrition. We analyzed mice in which the binding site for PPARγ was deleted from the promoter of the cyt...

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Библиографические подробности
Главные авторы: Hsieh, Chang-Wen, Millward, Carrie A., DeSantis, David, Pisano, Sorana, Machova, Jana, Perales, Jose C., Croniger, Colleen M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Nutrition 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777474/
https://ncbi.nlm.nih.gov/pubmed/19812223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.113092
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