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Effects of progesterone on motility and prostaglandin levels in the distal guinea pig colon

Progesterone (P4) inhibits the gastrointestinal muscle contraction by downregulating Gα(q/11) proteins that mediate contraction, by upregulating Gα(s) proteins that mediate relaxation, and by altering the pattern of cyclooxygenase (COX) enzymes and prostaglandins. We aimed to examine whether P4 trea...

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Библиографические подробности
Главные авторы: Xiao, Zuo Liang, Biancani, Piero, Behar, Jose
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777458/
https://ncbi.nlm.nih.gov/pubmed/20501437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00184.2009
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