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Dosage Regulation of the Active X Chromosome in Human Triploid Cells
In mammals, dosage compensation is achieved by doubling expression of X-linked genes in both sexes, together with X inactivation in females. Up-regulation of the active X chromosome may be controlled by DNA sequence–based and/or epigenetic mechanisms that double the X output potentially in response...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777382/ https://ncbi.nlm.nih.gov/pubmed/19997486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000751 |
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