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Novel Rank-Based Statistical Methods Reveal MicroRNAs with Differential Expression in Multiple Cancer Types

BACKGROUND: microRNAs (miRNAs) regulate target genes at the post-transcriptional level and play important roles in cancer pathogenesis and development. Variation amongst individuals is a significant confounding factor in miRNA (or other) expression studies. The true character of biologically or clin...

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Main Authors: Navon, Roy, Wang, Hui, Steinfeld, Israel, Tsalenko, Anya, Ben-Dor, Amir, Yakhini, Zohar
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777376/
https://ncbi.nlm.nih.gov/pubmed/19946373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008003
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