Use of a Label-Free Quantitative Platform Based on MS/MS Average TIC to Calculate Dynamics of Protein Complexes in Insulin Signaling

A label-free quantification strategy including the development of in-house software (NakedQuant) to calculate the average TIC across all spectral counts in tandem affinity purification (TAP)-tagging liquid chromatography-mass spectrometry MS/MS (LC/MS/MS) experiments was applied to a large-scale stu...

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Autors principals: Yang, Xuemei, Friedman, Adam, Nagpal, Shailender, Perrimon, Norbert, Asara, John M.
Format: Artigo
Idioma:Inglês
Publicat: Association of Biomolecular Resource Facilities 2009
Matèries:
ABRF 2009 Selected Presentations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777340/
https://ncbi.nlm.nih.gov/pubmed/19949701
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