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Propylthiouracil (PTU) Hepatoxicity in Children and Recommendations for Discontinuation of Use

Propylthiouracil (PTU) was introduced for clinical use in July 1947 for Graves' disease (GD) treatment. Over the 60 years that this medication has been used, reports of PTU-related liver failure and death have accumulated. On October 28, 2008, an expert panel evaluated PTU drug safety in childr...

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Detalhes bibliográficos
Main Authors: Rivkees, Scott A., Mattison, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777303/
https://ncbi.nlm.nih.gov/pubmed/19946400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/132041
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