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Impaired extinction of learned fear in rats selectively bred for high anxiety – evidence of altered neuronal processing in prefrontal-amygdala pathways

The impaired extinction of acquired fear is a core symptom of anxiety disorders, such as post-traumatic stress disorder, phobias or panic disorder, and is known to be particularly resistant to existing pharmacotherapy. We provide here evidence that a similar relationship between trait anxiety and re...

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Detalhes bibliográficos
Main Authors: Muigg, Patrik, Hetzenauer, Alfred, Hauer, Gabriele, Hauschild, Markus, Gaburro, Stefano, Frank, Elisabeth, Landgraf, Rainer, Singewald, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777258/
https://ncbi.nlm.nih.gov/pubmed/19019199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06511.x
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