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Protein flexibility: coordinate uncertainties and interpretation of structural differences

Valid interpretations of conformational movements in protein structures determined by X-ray crystallography require that the movement magnitudes exceed their uncertainty threshold. Here, it is shown that such thresholds can be obtained from the distance difference matrices (DDMs) of 1014 pairs of in...

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Autors principals: Rashin, Alexander A., Rashin, Abraham H. L., Jernigan, Robert L.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777169/
https://ncbi.nlm.nih.gov/pubmed/19923711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744490903145X
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