BMP4 regulates the hematopoietic stem cell niche

Bone morphogenetic protein 4 (BMP4) is required for mesoderm commitment to the hematopoietic lineage during early embryogenesis. However, deletion of BMP4 is early embryonically lethal and its functional role in definitive hematopoiesis is unknown. Consequently, we used a BMP4 hypomorph to investiga...

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Hlavní autoři: Goldman, Devorah C., Bailey, Alexis S., Pfaffle, Dana L., Al Masri, Azzah, Christian, Jan L., Fleming, William H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777124/
https://ncbi.nlm.nih.gov/pubmed/19759357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-206433
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