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Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma

OBJECTIVE: Independent studies have previously demonstrated that both the HIPK2 and BRAF genes are amplified and rearranged, respectively, in pilocytic astrocytomas (PAs). The purpose of this study was to further investigate the frequency of BRAF and HIPK2 alterations in PAs, the concordance of thes...

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Autori principali: Yu, J, Deshmukh, H, Gutmann, R J., Emnett, R J., Rodriguez, F J., Watson, M A., Nagarajan, R, Gutmann, D H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Academy of Neurology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777068/
https://ncbi.nlm.nih.gov/pubmed/19794125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181c0664a
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