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A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei

Sedoheptulose-7-phosphate isomerase (GmhA) converts d-sedoheptulose 7-­phosphate to d,d-heptose 7-phosphate. This is the first step in the biosynthesis pathway of NDP-heptose, which is responsible for the pleiotropic phenotype. This biosynthesis pathway is the target of inhibitors to increase the me...

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Detalhes bibliográficos
Main Authors: Kim, Mi-Sun, Shin, Dong Hae
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777036/
https://ncbi.nlm.nih.gov/pubmed/19923728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910903259X
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