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Molecular machines or pleiomorphic ensembles: signaling complexes revisited

Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues.

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Detalhes bibliográficos
Main Authors: Mayer, Bruce J, Blinov, Michael L, Loew, Leslie M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776906/
https://ncbi.nlm.nih.gov/pubmed/19835637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol185
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