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Comparison of Parametric and Bootstrap Method in Bioequivalence Test

The estimation of 90% parametric confidence intervals (CIs) of mean AUC and Cmax ratios in bioequivalence (BE) tests are based upon the assumption that formulation effects in log-transformed data are normally distributed. To compare the parametric CIs with those obtained from nonparametric methods w...

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Autors principals: Ahn, Byung-Jin, Yim, Dong-Seok
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776897/
https://ncbi.nlm.nih.gov/pubmed/19915699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.5.367
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