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Conjugating Methotrexate to magnetite (Fe(3)O(4)) nanoparticles via trichloro-s-triazine

Monodisperse Fe(3)O(4) nanoparticles (NPs) originally synthesized with a hydrophobic oleylamine capping ligand were made water soluble and conjugated to the anticancer drug Methotrexate (MTX) using a new chemistry based on the readily available linker trichloro-s-triazine (TsT). This new linker is m...

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Main Authors: Young, Kaylie L., Xu, Chenjie, Xie, Jin, Sun, Shouheng
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776745/
https://ncbi.nlm.nih.gov/pubmed/19915686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b902373a
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