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Exon sequences at the splice junctions affect splicing fidelity and alternative splicing

Identification of splice sites is essential for the expression of most eukaryotic genes, allowing accurate splicing of pre-mRNAs. The splice sites are recognized by the splicing machinery based on sequences within the pre-mRNA. Here, we show that the exon sequences at the splice junctions play a sig...

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Bibliographic Details
Main Authors: Crotti, Luciana B., Horowitz, David S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776460/
https://ncbi.nlm.nih.gov/pubmed/19855008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907948106
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