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The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma

GATA4 is a transcription factor that plays a role in regulating the normal development of many mesoderm and endoderm derived tissues, including the pancreas. Silencing of GATA4 mRNA expression by promoter methylation has been implicated in carcinogenesis of the ovary, lung and colorectum. By contras...

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Detalhes bibliográficos
Main Authors: Karafin, Matthew S., Cummings, Christopher T., Fu, Baojin, Iacobuzio-Donahue, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776266/
https://ncbi.nlm.nih.gov/pubmed/19918328
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