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Binding Kinetics of Bisintercalator Triostin A with Optical Tweezers Force Mechanics

The binding kinetics of the intercalative binding of Triostin A to λ-DNA was investigated by measuring the force extension response of the DNA-ligand complexes with an optical tweezers system. These force response curves, containing the information about different binding properties, were analyzed b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kleimann, Christoph, Sischka, Andy, Spiering, Andre, Tönsing, Katja, Sewald, Norbert, Diederichsen, Ulf, Anselmetti, Dario
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776255/
https://ncbi.nlm.nih.gov/pubmed/19917232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.001
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