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A Novel Method to Establish Microglia-Free Astrocyte Cultures: Comparison of Matrix Metalloproteinase Expression Profiles in Pure Cultures of Astrocytes and Microglia

Increased matrix metalloproteinase (MMP) proteolytic activity contributes to the pathogenesis of many neuroinflammatory and neurodegenerative conditions in the CNS. To fully understand this process, it is important to define the MMP expression profile of specific cell types, including the CNS-reside...

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Bibliographic Details
Main Authors: CROCKER, STEPHEN J., FRAUSTO, RICARDO F., WHITTON, J. LINDSAY, MILNER, RICHARD
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776034/
https://ncbi.nlm.nih.gov/pubmed/18449943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20689
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