Inferring within-patient HIV-1 evolutionary dynamics under anti-HIV therapy using serial virus samples with vSPA

BACKGROUND: Analysis of within-patient HIV evolution under anti-HIV therapy is crucial to a better understanding the possible mechanisms of HIV drug-resistance acquisition. The high evolutionary rate of HIV allows us to trace its evolutionary process in real time by analyzing virus samples serially...

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Hlavní autoři: Hasegawa, Naoki, Sugiura, Wataru, Shibata, Junko, Matsuda, Masakazu, Ren, Fengrong, Tanaka, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776027/
https://ncbi.nlm.nih.gov/pubmed/19863822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-360
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