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Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

BACKGROUND: Variation in genes involved in the innate immune response may play a role in the predisposition to colorectal cancer (CRC). Several polymorphisms of the CARD15 gene (caspase activating recruitment domain, member 15) have been reported to be associated with an increased susceptibility to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Möckelmann, Nikolaus, von Schönfels, Witigo, Buch, Stephan, von Kampen, Oliver, Sipos, Bence, Egberts, Jan Hendrik, Rosenstiel, Philip, Franke, Andre, Brosch, Mario, Hinz, Sebastian, Röder, Christian, Kalthoff, Holger, Fölsch, Ulrich R, Krawczak, Michael, Schreiber, Stefan, Bröring, Clemens Dieter, Tepel, Jürgen, Schafmayer, Clemens, Hampe, Jochen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776017/
https://ncbi.nlm.nih.gov/pubmed/19843337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-9-79
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