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Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model

BACKGROUND: Local inflammation associated with solid tumors commonly results from factors released by tumor cells and the tumor stroma, and promotes tumor progression. Cancer associated fibroblasts comprise a majority of the cells found in tumor stroma and are appealing targets for cancer therapy. H...

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Autors principals: Liao, Debbie, Luo, Yunping, Markowitz, Dorothy, Xiang, Rong, Reisfeld, Ralph A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775953/
https://ncbi.nlm.nih.gov/pubmed/19956757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007965
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