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Influence of Membrane CD25 Stability on T Lymphocyte Activity: Implications for Immunoregulation

BACKGROUND: CD25, a component of the IL-2 receptor, is important in T cell proliferation, activation induced cell death, as well as the actions of both regulatory (Treg) and effector (Teff) T cells. Recent genome wide association studies have implicated the CD25 locus as an important region for gene...

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Bibliografiska uppgifter
Huvudupphovsmän: Brusko, Todd M., Wasserfall, Clive H., Hulme, Maigan A., Cabrera, Roniel, Schatz, Desmond, Atkinson, Mark A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775921/
https://ncbi.nlm.nih.gov/pubmed/19956753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007980
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