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Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

BACKGROUND: Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders. Because neurons have been thought impermeable to immunoglobulins, however, such antibodies have been considered unable to enter neurons an...

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Detalhes bibliográficos
Main Authors: Hill, Kenneth E, Clawson, Susan A, Rose, John W, Carlson, Noel G, Greenlee, John E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775726/
https://ncbi.nlm.nih.gov/pubmed/19874605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-31
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