Homozygosity of the Polymorphism MICA5.1 Identifies Extreme Risk of Progression to Overt Adrenal Insufficiency among 21-Hydroxylase Antibody-Positive Patients with Type 1 Diabetes

Context: Autoimmunity associated with Addison’s disease (AD) can be detected by measuring 21-hydroxylase (21OH) autoantibodies. Subjects with type 1 diabetes (T1D) are at increased risk for AD. Genetic factors including HLA-DRB1*0404 and MICA have been associated with AD in populations with and with...

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Bibliografiset tiedot
Päätekijät: Triolo, Taylor M., Baschal, Erin E., Armstrong, Taylor K., Toews, Carrie S., Fain, Pamela R., Rewers, Marian J., Yu, Liping, Miao, Dongmei, Eisenbarth, George S., Gottlieb, Peter A., Barker, Jennifer M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Endocrine Society 2009
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775653/
https://ncbi.nlm.nih.gov/pubmed/19820007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2009-1308
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