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Complex selection on 5′ splice sites in intron-rich organisms

In contrast to the typically streamlined genomes of prokaryotes, many eukaryotic genomes are riddled with long intergenic regions, spliceosomal introns, and repetitive elements. What explains the persistence of these and other seemingly suboptimal structures? There are three general hypotheses: (1)...

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Detalhes bibliográficos
Main Authors: Irimia, Manuel, Roy, Scott William, Neafsey, Daniel E., Abril, Josep F., Garcia-Fernandez, Jordi, Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775602/
https://ncbi.nlm.nih.gov/pubmed/19745111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089276.108
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