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Fungiform papilla pattern: EGF regulates inter - papilla lingual epithelium and decreases papilla number via PI3K/Akt, MEK/ERK and p38 MAPK signaling

Fungiform papillae are epithelial taste organs that form on the tongue, requiring differentiation of papillae and inter-papilla epithelium. We tested roles of epidermal growth factor (EGF) and the receptor EGFR in papilla development. Developmentally, EGF was localized within and between papillae wh...

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Bibliografiske detaljer
Main Authors: Liu, Hong-Xiang, Henson, Bradley S., Zhou, Yanqiu, D’Silva, Nisha J., Mistretta, Charlotte M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775556/
https://ncbi.nlm.nih.gov/pubmed/18729215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21657
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