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Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795

One approach for the identification of therapeutic agents for Alzheimer's disease has focused on the research of α7 nAChR-selective agonists such as the partial agonists 3-(4-hydroxy,2-methoxybenzylidene)anabaseine (4OH-GTS-21) and, more recently, 2-[2-(4-bromophenyl)-2-oxoethyl]-1-methyl pyrid...

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Autors principals: López-Hernández, Gretchen Y., Thinschmidt, Jeffrey S., Morain, Philippe, Trocme-Thibierge, Caryn, Kem, William R., Soti, Ferenc, Papke, Roger L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775526/
https://ncbi.nlm.nih.gov/pubmed/19705574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.01.011
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