Inhibition of VEGF or TGF-β signaling activates endothelium and increases leukocyte rolling

OBJECTIVE: Motivated by the central roles that VEGF and TGF-β play in the assembly and maintenance of the vasculature, we examined the impact of systemic VEGF or TGF-β signal inhibition on endothelial activation as detected by leukocyte-endothelial interactions. METHODS AND RESULTS: VEGF or TGF-β in...

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Main Authors: Walshe, Tony E., Dole, Vandana S., Maharaj, Arindel S.R., Patten, Ian S., Wagner, Denisa D., D’Amore, Patricia A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775449/
https://ncbi.nlm.nih.gov/pubmed/19461051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.186742
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