Enhanced Calcium Buffering in F344 Rat Cholinergic Basal Forebrain Neurons Is Associated With Age-Related Cognitive Impairment

Alterations in neuronal Ca(2+) homeostasis are important determinants of age-related cognitive impairment. We examined the Ca(2+) influx, buffering, and electrophysiology of basal forebrain neurons in adult, middle-aged, and aged male F344 behaviorally assessed rats. Middle-aged and aged rats were c...

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Bibliographic Details
Main Authors: Murchison, David, McDermott, Angelika N., LaSarge, Candi L., Peebles, Kathryn A., Bizon, Jennifer L., Griffith, William H.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775378/
https://ncbi.nlm.nih.gov/pubmed/19675291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00301.2009
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