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α-Actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca(2+)-activated K(+) channel (SK2 channel)

The importance of proper ion channel trafficking is underpinned by a number of channel-linked genetic diseases whose defect is associated with failure to reach the cell surface. Conceptually, it is reasonable to suggest that the function of ion channels depends critically on the precise subcellular...

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Detalhes bibliográficos
Main Authors: Lu, Ling, Timofeyev, Valeriy, Li, Ning, Rafizadeh, Sassan, Singapuri, Anil, Harris, Todd R., Chiamvimonvat, Nipavan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775294/
https://ncbi.nlm.nih.gov/pubmed/19815520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908207106
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