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α-Actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca(2+)-activated K(+) channel (SK2 channel)

The importance of proper ion channel trafficking is underpinned by a number of channel-linked genetic diseases whose defect is associated with failure to reach the cell surface. Conceptually, it is reasonable to suggest that the function of ion channels depends critically on the precise subcellular...

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Hlavní autoři: Lu, Ling, Timofeyev, Valeriy, Li, Ning, Rafizadeh, Sassan, Singapuri, Anil, Harris, Todd R., Chiamvimonvat, Nipavan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775294/
https://ncbi.nlm.nih.gov/pubmed/19815520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908207106
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