Natural Variation within the Neuronal Nicotinic Acetylcholine Receptor Cluster on Human Chromosome 15q24: Influence on Heritable Autonomic Traits in Twin Pairs

Nicotinic acetylcholine receptors (nAChRs) are combinations of subunits arranged as pentamers encircling a central cation channel. At least nine α and four β subunits are expressed in the central and peripheral nervous systems; their presence in autonomic ganglia, the adrenal medulla, and central ne...

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Main Authors: Rana, Brinda K., Wessel, Jennifer, Mahboubi, Vafa, Rao, Fangwen, Haeller, Jeannine, Gayen, Jiaur R., Eskin, Eleazar, Valle, Anne M., Das, Madhusudan, Mahata, Sushil K., Taupenot, Laurent, Stridsberg, Mats, Talley, Todd T., Ziegler, Michael G., Smith, Douglas W., Schork, Nicholas J., O'Connor, Daniel T., Taylor, Palmer
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2009
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775266/
https://ncbi.nlm.nih.gov/pubmed/19671882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.157271
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