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Extended Methamphetamine Self-Administration in Rats Results in a Selective Reduction of Dopamine Transporter Levels in the Prefrontal Cortex and Dorsal Striatum Not Accompanied by Marked Monoaminergic Depletion

Chronic abuse of methamphetamine leads to cognitive dysfunction and high rates of relapse, paralleled by significant changes of brain dopamine and serotonin neurotransmission. Previously, we found that rats with extended access to methamphetamine self-administration displayed enhanced methamphetamin...

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Main Authors: Schwendt, Marek, Rocha, Angelica, See, Ronald E., Pacchioni, Alejandra M., McGinty, Jacqueline F., Kalivas, Peter W.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775260/
https://ncbi.nlm.nih.gov/pubmed/19648469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.155770
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