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Schizosaccharomyces pombe Cds1(Chk2) regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60

The Schizosaccharomyces pombe rad60 gene is essential for cell growth and is involved in repairing DNA double-strand breaks. Rad60 physically interacts with, and is functionally related to, the structural maintenance of chromosomes 5 and 6 protein complex (Smc5/6). Rad60 is phosphorylated in respons...

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Autors principals: Miyabe, Izumi, Morishita, Takashi, Shinagawa, Hideo, Carr, Antony M.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774987/
https://ncbi.nlm.nih.gov/pubmed/19755492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046508
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