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Presentation of human T cell leukemia virus type 1 (HTLV-1) Tax protein by dendritic cells: the underlying mechanism of HTLV-1-associated neuroinflammatory disease

HTLV-1 is the etiologic agent of a debilitating neurologic disorder, HAM/TSP. This disease features a robust immune response including the oligoclonal expansion of CD8(+) CTLs specific for the viral oncoprotein Tax. The key pathogenic process resulting in the proliferation of CTLs and the presentati...

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Main Authors: Manuel, Sharrón L., Schell, Todd D., Acheampong, Edward, Rahman, Saifur, Khan, Zafar K., Jain, Pooja
格式: Artigo
語言:Inglês
出版: The Society for Leukocyte Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774881/
https://ncbi.nlm.nih.gov/pubmed/19656902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0309172
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