ACUTE INDUCTION OF EPILEPTIFORM DISCHARGES BY PILOCARPINE IN THE IN VITRO ISOLATED GUINEA-PIG BRAIN REQUIRES ENHANCEMENT OF BLOOD–BRAIN BARRIER PERMEABILITY

Systemic application of the muscarinic agonist, pilocarpine, is commonly utilized to induce an acute status epilepticus that evolves into a chronic epileptic condition characterized by spontaneous seizures. Recent findings suggest that the status epilepticus induced by pilocarpine may be triggered b...

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Autors principals: UVA, L., LIBRIZZI, L., MARCHI, N., NOE, F., BONGIOVANNI, R., VEZZANI, A., JANIGRO, D., DE CURTIS, M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774816/
https://ncbi.nlm.nih.gov/pubmed/18082973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.10.037
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