IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT-3 and suppression of HuR

Persistent inflammatory response has adverse effects on left ventricular (LV) function and remodeling following acute myocardial infarction (AMI). We hypothesized that suppression of inflammation with IL-10 treatment attenuates LV dysfunction and remodeling after AMI. After the induction of AMI, mic...

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Detalhes bibliográficos
Main Authors: Krishnamurthy, Prasanna, Rajasingh, Johnson, Lambers, Erin, Qin, Gangjian, Losordo, Douglas W., Kishore, Raj
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774810/
https://ncbi.nlm.nih.gov/pubmed/19096025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.188243
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